There was one problem, however: it substantially increased the incidence of heart attack and stroke. Merck is alleged to have withheld critical data that surfaced in that could have enabled the FDA to take action over Vioxx, potentially preventing many deaths.
The company shopped around for compliant academics who would attach their names to papers, written by Merck employees, and then submitted them to leading medical journals to give the faulty research creditability. It is believed the settlement will cover the majority of litigants in the US. In Australia, the Federal Court last week overturned a ruling that could have seen up to former Vioxx users who suffered heart attacks to claim compensation from Merck. The court case revealed that the company had made a hit list of doctors, researchers and academics that were critical of Vioxx.
Interference with academic appointments and withdrawing funding were also alleged to have occurred. We should, however, not be surprised about the behavior of Merck, as it is the product of numerous perverse incentives provided by the flawed patent system. Maurice Hilleman. MEFOXIN was indicated for the treatment of many infections caused by certain bacteria, including gram-positive and gram-negative pathogens.
Merck introduced lovastatin, the first of the statin family of medicines to be approved by the FDA. It emerged from decades of study by scientists in the U. Roy Vagelos announced Merck's commitment to donate Mectizan - as much as needed for as long as needed - with the goal to help eliminate river blindness. In order to reach this goal, Merck leaders recognized that many organizations with unique skills would need to work together as a team.
Thus, the Mectizan Donation Program MDP was created as a groud-breaking public-private partnership that becomes influential in the development of a number of other drug donation programs. Prior to the FDA approval in , in conjunction with the U. Through this program, Merck made the drug available at no cost to selective patients before it was commercially available. It was the product of nearly twenty years of research conducted at our Merck Frosst discovery hub in Kirkland, Canada, into a new class of asthma medicines called leukotriene blockers.
Merck and Schering-Plough completed a merger and began combined operations. The purchase made the company the second largest pharmaceutical company in United States by revenue. In , one woman died every two minutes during childbirth and pregnancy. Many of these deaths were preventable. In response, we launched Merck for Mothers, a global initiative with partners to improve the health and well-being of women before, during and after pregnancy and childbirth.
As of , the effort has reached more than nine million women globally in 48 countries. It had previously received breakthrough therapy designation from the FDA.
From Guinea to the Democratic Republic of the Congo DRC , the world was dealing with the largest and most complex Ebola outbreaks since the virus was first discovered in As the outbreaks remained a global health challenge, scientists from Merck, along with numerous external collaborators from all sectors, remained at the forefront of the efforts to address this deadly disease. In , the U. The Merck Index is an encyclopedia of chemicals, drugs, and biological information for use by health care professionals and scientists.
It has also published other references including The Merck Manual and The Merck Veterinary Manual and other textbooks still in use today. In , during the Vioxx scandal, Merck was exposed for fraudulent publishing. It was discovered that the Australian division of the company had paid Elsevier, a medical publishing platform an undisclosed amount to produce eight issues of a fraudulent medical journal.
The journal was found to have reprinted Merck-friendly articles but never disclosed that it was a sponsored publication. The CEO of Elsevier later apologized, admitting that the practices were false and should never have been allowed.
They have manufactured over-the-counter medications like asthma and allergy medication as well as vaccines and diabetic medication for animals. Some notable products include sunscreen, hair-growth medication Propecia, antihistamine Claritin, and HPV vaccine Gardasil. The company produced the first commercial smallpox vaccine in the U. S and provided 4. This facility closed in July and the company was renamed as Merck Canada in In , Merck voluntarily withdrew Vioxx. The most well-known of which are allergy drugs Claritin and Clarinex, plus the anti-cholesterol drug Vytorin and brain tumour drug Temodar.
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